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Low Testosterone & Heart Disease

We think you will find some helpful information on these sites concerning Low Testosterone and Heart Disease.

MyHeartCentral.com - "Testosterone for Heart Health?"

Green Health Spot - "Men with Low Testosterone Have the Greatest Heart Disease Risk"

Heart Disease Prevention - "Is Male's Testosterone Levels Linked to Cardiovascular Disease Death?"

Reuters - "High Testosterone Linked to Men's Lower Death Risk"

Darrow Wellness Institute - "Testosterone for Men"

Harvard University Gazette - "Study of Testosterone Replacement Therapy Not Linked to Prostate Cancer, Heart Disease Risk"

The Free Library - "Does Testosterone Fight Artery Disease?"

Natural News - "Hormones Part VI: Low Testosterone in Men Linked to Huge Increase in Risk of Death"

Also, here is an interesting study about how testosterone may help prevent heart attacks...

Abstract

Chronic heart failure is common and can be described as a syndrome characterized by impairment of cardiac function associated with a maladaptive metabolic and neurohormonal axis. The thesis that testosterone replacement therapy may be helpful as a treatment for chronic heart failure may seem at first to be unlikely. Testosterone therapy is widely believed to be deleterious to the cardiovascular system and there is a common misconception that the excess of ischaemic heart disease in young and middle-aged males compared to females is a direct effect of endogenous serum testosterone levels. In this chapter we will present the published evidence of the effects of endogenous and therapeutic testosterone on the heart and the human cardiovascular system with an emphasis on the pathologic syndrome of chronic heart failure. There is developing evidence that of all morbid populations, patients with chronic heart failure in particular are likely to benefit from testosterone treatment since the natural history is that of progressive disordered metabolism with catabolic excess and androgen imbalance.

What role does testosterone play?

Just how important is testosterone for preventing heart disease in men?

Just 20 years ago, this question wouldn't have even been asked. Traditional teaching was that, because men develop heart disease earlier than females (by 10 years), testosterone must therefore cause heart disease.

But, observations accumulated since then have turned this misconception topsy-turvy:
    - Not only does testosterone not cause heart disease, it may in fact be protective.
    - Testosterone levels peak in a male's 20s during his reproductive prime. That's also the period of a man's greatest physical capacity, muscle mass, physical energy, libido, and stamina.
    - Starting at age 30, testosterone levels diminish.
    - By the time a man reaches his 70s, testosterone has dropped to low, sometimes unmeasurable, levels.

Coincidentally, a male's increasing risk for heart disease with aging parallels the decline in testosterone. Indeed, several studies have connected lower testosterone blood levels with greater likelihood of heart attack. An 11,000-participant European study (EPIC Norfolk), for instance, showed that the men with the highest testosterone levels (natural, without supplementation) had 40% fewer deaths from heart attack and cancer. An NIH-sponsored study (The Aging in the Chianti Area Study) showed a 48% higher mortality rate (cardiovascular and cancer) in men with low testosterone. In another study, a marked deficiency of testosterone ("hypogonadism") was found in 25% of men with coronary disease (history of heart attack or major heart procedures).

Several other studies in the U.S. and elsewhere have confirmed similar observations: The lower the testosterone, the greater the likelihood of heart attack.

How might testosterone be related to heart disease risk? Let's look at some of the observations that have been made...

Testosterone increases the production of the natural arterial dilator, nitric oxide, and suppresses growth of smooth muscle cells in arteries (a constituent of plaque). Lack of testosterone does the opposite.

Improvement in abnormal resistance to insulin-This is the essential phenomena behind pre-diabetes and metabolic syndrome. Men with pre-diabetes and diabetes have low testosterone much more frequently than men without these conditions.

Heart disease is, to A dramatic reduction in inflammatory proteins degree, a consequence of a large inflammatory responses. Lack of testosterone permits an explosion in inflammatory responses.

Low testosterone levels also lead to loss of muscle mass, increased abdominal fat, and reduced libido. Mood disruptions develop, with deeper swings into blue, depressed feelings, struggles with feeling beaten and overwhelmed, and fatigue. Reduced concentration, irritability, passivity, loss of interest in activities, and even hypochondria can also result, changes that often become insidiously perceptible after a man passes beyond his mid-40's. Some call this time the "male menopause" or "andropause." Though not as visible as a woman's transition to menopause, the changes are indeed distinct. Since there's no external cue like cessation of a woman's menstrual period, most men simply dismiss the changes as "getting old."


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